DiaPharma APC Resistance clotting assay test kit


Introduction | Biochemistry | Clinical Aspects | Key Reports | PubMed Abstracts | References | Assay Methods | APC Resistance Phenotyping | Factor V Mutation ScreeningFAQ


Occurrence of gene mutations in factor V Leiden, prothrombin and methylenetetra-hydrofolate reductase in patients with pre-eclampsia

Prochazka M, Krcova V, Kudela M, Slavik L.

Ceska Gynekol. 2003 May;68(3):162-6. Czech.

PMID: 12879654


The effect of lupus anticoagulant in the second-generation assay for activated protein C resistance.

Ragland BD, Reed CE, Eiland BM, Tichenor PH, Hudson CL, Fritsma GA, Adler BK, Marques MB.

Am J Clin Pathol. 2003 Jan;119(1):66-71.

PMID: 12520699


Reduced factor V concentration and altered FV1/FV2 ratio do not fully explain R2-associated APC-resistance.

Govers-Riemslag JW, Castoldi E, Nicolaes GA, Tans G, Rosing J.

Thromb Haemost. 2002 Sep;88(3):444-9.

PMID: 12353074


Activated protein C resistance, the factor V Leiden mutation, and a laboratory testing algorithm.

Van Cott EM, Soderberg BL, Laposata M.

Arch Pathol Lab Med. 2002 May;126(5):577-82. Review.

PMID: 11958664


Proteolysis of protein C in pooled normal plasma and purified protein C by activated protein C (APC).

Hassouna H, Quinn C.

Biophys Chem. 2002 Feb 19;95(2):109-24.

PMID: 11897150


The routine coagulation tests along with activated protein C resistance (APC-R) in population of women applying for oral contraceptives

Kostecka I, Dabrowska M, Osada J, Suchowierska M, Wolczynski S.

Przegl Lek. 2001;58(12):1038-40. Polish.

PMID: 12041017


Impact of oral contraceptive use on APC-resistance: a prospective, randomized clinical trial with three low-dose preparations.

Endrikat J, Noah M, Gerlinger C, Bannemerschult R, Junge W, Ruebig A, Schmidt W, Dusterberg B.

Contraception. 2001 Oct;64(4):217-22.

PMID: 11747870


Association of the R485K polymorphism of the factor V gene with poor response to activated protein C and increased risk of coronary artery disease in the Chinese population.

Le W, Yu JD, Lu L, Tao R, You B, Cai X, Cao WJ, Huang W, He RM, Zhu DL, Chen Z, Gong LS.

Clin Genet. 2000 Apr;57(4):296-303.

PMID: 10845571


Resistance to activated protein C and FV leiden mutation in patients with a history of acute myocardial infarction or primary hypertension.

Makris TK, Krespi PG, Hatzizacharias AN, Gialeraki AE, Anastasiadis G, Triposkiadis FK, Mandalaki T, Kyriakidis MK.

Am J Hypertens. 2000 Jan;13(1 Pt 1):61-5.

PMID: 10678272


Activated protein C resistance and factor V Leiden mutation are independent risk factors for venous thromboembolism.

Rodeghiero F, Tosetto A.

Ann Intern Med. 1999 Apr 20;130(8):643-50.

PMID: 10215560


Factor V Leiden, activated protein C resistance, and retinal vein occlusion.

Ciardella AP, Yannuzzi LA, Freund KB, DiMichele D, Nejat M, De Rosa JT, Daly JR, Sisco L.

Retina. 1998;18(4):308-15.

PMID: 9730172


Evaluation of a modified APTT-based method for determination of APC resistance in plasma from patients on heparin or oral anticoagulant therapy.

Hall C, Andersson NE, Andras M, Zetterberg U, Rosen S.

Thromb Res. 1998 Mar 1;89(5):203-9.

PMID: 9645913


Activated protein C resistance assay performance: improvement by sample dilution with factor V-deficient plasma.

Strobl FJ, Hoffman S, Huber S, Williams EC, Voelkerding KV.

Arch Pathol Lab Med. 1998 May;122(5):430-3.

PMID: 9593344


Activated protein C resistance–a major risk factor for thrombosis.

Rosen SB, Sturk A.

Eur J Clin Chem Clin Biochem. 1997 Jul;35(7):501-16. Review.

PMID: 9263726


Improved characteristics of APC-resistance assay: Coatest APC Resistance by predilution of samples with factor V deficient plasma.

Kapiotis S, Quehenberger P, Jilma B, Handler S, Pabinger-Fasching I, Mannhalter C, Speiser W.

Am J Clin Pathol. 1996 Nov;106(5):588-93.

PMID: 8929467


Multicenter evaluation of a kit for activated protein C resistance on various coagulation instruments using plasmas from healthy individuals. The APC Resistance Study Group.

Rosen S, Johansson K, Lindberg K, Dahlback B.

Thromb Haemost. 1994 Aug;72(2):255-60.

PMID: 7831662

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